I know when we're young we tend to make mistakes and some can cost us dearly. However, after we've made a mistake hopefully we'll learn and not make the same mistake again and again. I know many young girls (and guys) who obviously made a mistake about their partner when they were young. And hopefully they will take more time and utilize their previous experience to make a better decision the next time.
But if you paid attention to these particular women and their discussion you'd think they'll never learn. They were old enough, wise enough, and had enough experience to choose carefully when they married their current spouse. But they still screwed up. Or so they think.
Does this mean that some people will never enjoy a long satisfactory relationship their whole lives? It makes you wonder. And if not, why not? Is there something in their upbringing that created this issue.
I would always suggest that someone should try their best to make a relationship work because the grass is NOT always greener. But if it ain't happening AND there are no children involved, move on! And use better judgement the next time.